CLOSTRIDIUM BIFERMENTANS PDF

Can J Infect Dis Med Microbiol. Mar-Apr;26(2) Empyema caused by Clostridium bifermentans: A case report. Edagiz S(1), Lagace-Wiens P(2), Embil . Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of resistance of this organism to. We report a case of recurrent Clostridium bifermentans bacteremia resulting in metastatic osteomyelitis involving the sacrum, spine, and ribs. The emergence of .

Author: Voodoora Mazular
Country: Tunisia
Language: English (Spanish)
Genre: Personal Growth
Published (Last): 14 July 2010
Pages: 87
PDF File Size: 2.25 Mb
ePub File Size: 15.73 Mb
ISBN: 287-4-79184-401-3
Downloads: 2054
Price: Free* [*Free Regsitration Required]
Uploader: Dailkis

This organism is infrequently reported as a cause of infection in humans, and older publications tended to regard it as nonpathogenic.

Clin Microbiol Rev ; Sem Hop ; Empyema fluid obtained at the time of surgery was submitted to the microbiology laboratory.

Repeat chest radiography revealed a loculated right-sided pneumothorax with a small amount of fluid remaining in the empyema cavity.

Clostridium septicum empyema in an immunocompetent woman. Potential conflicts of interest. This article has been cited by other articles in PMC. Furthermore, beforeclostridiuum two cases of human infection due to this organism had been reported 78. Author information Copyright and License information Disclaimer.

It is found in sewage, soil, and occasionally the intestinal flora of humans. A review from a rural area. Septic arthritis of the knee due to Clostridium bifermentans. An exceptional agent of endocarditis.

Kirby2, 3 and Mary Albrecht 1, 4. Although polymerase chain reaction PCR assay specific for C sordellii was negative, wide-range 16 S PCR assay of endometrial tissue was positive for Bifermmentans bifermentans. Ryan K, Ray C.

Thus, to remove potential toxin, empiric plasmapheresis clostridiim started on hospital day 3, which showed immediate improvement in hemodynamics, and fluid was able to be removed with continuous venovenous hemofiltration. Blood cultures aerobic and anaerobic were negative.

  ASTM D413 PDF

Open in a separate window.

Empyema caused by Clostridium bifermentans: A case report.

Clostridium bifermentans bacteremia with metastatic osteomyelitis. Am Rev Respir Dis ; On respiratory examination, decreased air entry was noted in the right lower and middle lobes. Lung tissue obtained at the time of this surgery for aerobic and anaerobic bacterial culture was found to be sterile.

The patient also complained of sharp right-sided pleuritic chest pain, as well as right upper quadrant abdominal pain associated with deep breathing. C bifermentans was recovered from blood and pleural fluid cultures. Clostridium sordellii also elaborates lethal toxin, which undermines the actin cytoskeleton at the cellular level, and is believed through this activity to compromise endothelial barrier integrity [ 18 ].

However, in more recent reports, C bifermentans has been documented as a cause of septic arthritis, osteomyelitis, soft tissue infection, abdominal biferrmentans, brain abscess, bacteremia and endocarditis. Author information Article notes Copyright and License information Disclaimer. J Clin Microbiol ; Report of a case caused by Clostridium bifermentans and review of the literature.

Abdominal abscess due to Cardiobacterium hominis and Clostridium bifermentans. Histopathology showed infection of the uterus, a site of infection not previously described.

Clostridium bifermentans (Weinberg and Seguin) Bergey et al. ATCC &reg

They may be found in soil, sewage, marine sediment and feces 23. Clostridium bifermentans Scientific classification Kingdom: Isolation of Clostridium in human infections: In somewhat dated animal studies involving mice and guinea pigs, C bifermentans did not demonstrate any lethal or dermatonecrotic properties 46.

Abdominal exam was notable for obesity but was otherwise benign. Older publications tended to regard C bifermentans as nonpathogenic 46. The constellation of findings in our patient severe capillary leak, profound leukocytosis and hemoconcentration, and improvement with plasmapheresis was very suspicious for C sordellii. C bifermentans has been described as a cause of septic arthritis, liver abscess following blunt abdominal trauma, abdominal abscess in association with Cardiobacterium hominisdelayed brain abscess due to a retained foreign body, metastatic osteomyelitis, soft tissue infection and endocarditis 79 — Anaerobic infections of war wounds in the Middle East.

  BUILDING TELEPHONY SYSTEMS WITH OPENSIPS PDF

Empyema caused by Clostridium bifermentans: A case report

Infect Immun ; Positive immunohistochemical staining dark pink for Clostridium species within areas of endometrial necrosis. Clostridium bifermentansEmpyema, Pneumonia. She subsequently deteriorated in hospital, with repeat chest radiography demonstrating pulmonary infiltrates and a pneumothorax that appeared to communicate with a cavitary lesion in the chest.

Clostridial bacteremia in the community hospital. C bifermentans is an anaerobic, spore-forming, Gram-positive bacillus. Alternatively, the infection may have occurred secondary to aspiration, although the patient did not have any risk factors for aspiration specifically identified. Twenty-nine days after the initial surgical procedure 44 days postadmissionthe patient was taken back to the operating room for a second thoracotomy, right rib resection and empyema drainage.

Moreover, within the Clostridium phylogeny, C bifermentans and C sordellii are closely related and were not identified as separate species until [ 21 ]. A chest tube was placed, and empirical antimicrobial therapy with a combination of levofloxacin and metronidazole was initiated. Jonsson et al 24 described a year-old man who presented with fever, cough and pleuritic chest pain.